ABSTRACT
INTRODUCTION: Asymptomatic carriers (AC) of the new SARS-CoV-2 represent an important source of spread for COVID-19. Early diagnosis of these cases is a powerful tool to control the pandemic. Our objective was to characterise patients with AC status and identify associated sociodemographic factors. METHODS: Using a cross-sectional design and the national database of daily occurrence of COVID-19, we characterised both socially and demographically all ACs. Additional correspondence analysis and logistic regression model were performed to identify characteristics associated with AC state (OR, 95% CI). RESULTS: 76.162 ACs (12.1%; 95% CI 12.0% to 12.2%) were identified, mainly before epidemiological week 35. Age≤26 years (1.18; 1.09 to 1.28), male sex (1.51; 1.40 to 1.62), cases imported from Venezuela, Argentina, Brazil, Germany, Puerto Rico, Spain, USA or Mexico (12.6; 3.03 to 52.5) and autochthonous cases (22.6; 5.62 to 91.4) increased the risk of identifying ACs. We also identified groups of departments with moderate (1.23; 1.13 to 1.34) and strong (19.8; 18.6 to 21.0) association with ACs. CONCLUSION: Sociodemographic characteristics strongly associated with AC were identified, which may explain its epidemiological relevance and usefulness to optimise mass screening strategies and prevent person-to-person transmission.
Subject(s)
COVID-19/epidemiology , Carrier State/epidemiology , Adult , COVID-19/diagnosis , COVID-19/transmission , Carrier State/diagnosis , Carrier State/transmission , Colombia , Cross-Sectional Studies , Databases, Factual , Female , Humans , Male , Middle Aged , Pandemics , SARS-CoV-2ABSTRACT
The mean percentage of cryptogenic strokes among ischemic strokes is 31%, of which one-third may be associated with patent foramen ovale. The foramen ovale is required for blood flow through the fetal atrial septum. It is formed as of the fourth week of gestation, and this leads to right-left interatrial shunt that allows the passage of oxygenated blood to systemic circulation. In 75% of cases, its closure is complete by 2 years of age, but it may persist in 25% of patients. We present the case of a patient with paradoxical embolism in the lower extremities and ischemic stroke in the clinical context of a patent foramen ovale.
ABSTRACT
Se trata de un caso clínico de un adolescente masculino de 15 años de edad remitido del municipio de Arauca, Arauca Colombia por un cuadro clínico de hematuria macroscópica, equimosis y gingivorragia con antecedente de contacto previo con orugas de la familia Saturniidae. Presentaba prolongación de los tiempos de coagulación y disminución del fibrinógeno. El diagnóstico fue establecido por la anamnesis, las manifestaciones clínicas y los reportes de laboratorio. Las medidas terapéuticas tuvieron éxito. Las características fisiopatológicas y clínicas del accidente lonómico serán revisadas.
This is a case report of a 15 years old male teenager referred from the municipality of Arauca, Arauca Colombia by a clinical picture of macroscopic hematuria, bruising and gingivorrhagia with a history of previous contact with caterpillars of the family saturniidae. clotting times were prolonged and fibrinogen was decreased. The diagnosis was established by history, clinical manifestations and laboratory reports. Therapeutic measures were successful. Pathophysiological and clinical characteristics of the lonimia accident have been reviewed.
